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Psychological dependence is primarily characterized by an emotional or mental need to use a substance, rather than physical symptoms. This concept focuses on the behaviors, thoughts, and feelings that compel an individual to engage in substance use due to their psychological state. People who experience psychological dependence may feel a craving for the substance, often using it as a means to cope with stress, anxiety, or other emotional challenges.

This distinguishes it from other forms of dependence that are more closely related to physical aspects, such as withdrawal symptoms or the need for increased dosages, which are more indicative of physical dependence. Understanding psychological dependence is critical in fields such as addiction counseling and treatment, as it addresses the mental triggers and emotional challenges that contribute to substance use.